专利名称:Methods of regulating differentiation in
stem cells
发明人:Alice Marie Pebay,Martin Frederick Pera申请号:US10657703申请日:20030909
公开号:US20040214319A1公开日:20041028
摘要:The present invention provides methods, media and compositions capable ofmodulating the differentiation of stem cells. Applicants have discovered that agonists oflysophospholipid receptors and ligands of class III tyrosine kinase receptors are useful inpreventing the spontaneous differentiation of stem cells. The ligands and agonists maybe used alone, or in combination where they have a synergistic effect. Also provided arecells produced using the methods and media, and methods of treating stem cell relateddiseases using the compositions described herein. Methods of identifying compoundsuseful in finding other agents useful in the modulation of stem cell differentiation arealso disclosed.
申请人:PEBAY ALICE MARIE,PERA MARTIN FREDERICK
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