专利名称:Derivatives of bicyclic amino acids, process
for their preparation, agents containingthem and their use, as well as bicyclic aminoacids as intermediates, and process forpreparing them
发明人:Urbach, Hansjörg, Dr.,Henning, Rainer,
Dr.,Teetz, Volker, Dr.,Geiger, Rolf, Prof.Dr.,Becker, Reinhard, Dr.,Gaul, Holger
申请号:EP82112007.8申请日:19821224公开号:EP0084164A2公开日:19830727
摘要:the invention relates to cis, exo - and trans compounds of the formula i in the n= 0, 1 or 2, r1 = hydrogen, possibly by amino, acylamino or benzoylamino substituiertesalkyl, alkenyl, cycloalkyl, cycloalkenyl, cycloalkylalkyl,aryl or aryl teilhydriertes,
respectively by alkyl, or halogen substituted alkoxy can be, as referred to above in aryi -rest substituiertes aralkyl, a mono - orbicyclischen sulfur or oxygen and \\/ or nitrogenheterocyclenrest or a side chain of a naturally occurring amino acid, r2 = hydrogen, alkyl,alkenyl or aralkyl,y = hydrogen or hydroxy, r = hydrogen or y and z = combined oxygenand x = alkyl, alkenyl, cycloalkyl (c1 - c4), - alkyl (c1 - c4) - alkoxy, hydroxy, halogen, nitro,amino.(c1 - c4) - alkylamino.di - (c1 - c4) alkylamino or methylendioxy mono, di - ortrisubstituiertes aryl, or lndol 3 yl, methods for their manufacturethe containing meansand its use, as well as new bicyclische amino acids as intermediate, and their production.
申请人:HOECHST AKTIENGESELLSCHAFT
地址:65926 Frankfurt am Main DE
国籍:DE
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