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Method for increasing efficiency or specificity of

2020-11-07 来源:乌哈旅游
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专利名称:Method for increasing efficiency or

specificity of hybridization between PNAprobes immobilized on support and targetnucleic acids

发明人:Heekyung Park,Jaejin Choi申请号:US12449692申请日:20080222公开号:US08252533B2公开日:20120828

摘要:Disclosed are a process for increasing efficiency or specificity of hybridizationbetween peptide nucleic acid (PNA) probes immobilized on a support and target nucleicacids, which comprises the step of fragment the target nucleic acids to reduce the size ofthe target nucleic acids, or selectively degrading the target nucleic acids which mismatchwith the PNA probes, in the hybridization reaction between the PNA probes supportedon a support and the target nucleic acids; and a composition and a kit therefor.

申请人:Heekyung Park,Jaejin Choi

地址:Daejeon KR,Daejeon KR

国籍:KR,KR

代理机构:Clark & Brody

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