专利名称:Method for increasing efficiency or
specificity of hybridization between PNAprobes immobilized on support and targetnucleic acids
发明人:Heekyung Park,Jaejin Choi申请号:US12449692申请日:20080222公开号:US08252533B2公开日:20120828
摘要:Disclosed are a process for increasing efficiency or specificity of hybridizationbetween peptide nucleic acid (PNA) probes immobilized on a support and target nucleicacids, which comprises the step of fragment the target nucleic acids to reduce the size ofthe target nucleic acids, or selectively degrading the target nucleic acids which mismatchwith the PNA probes, in the hybridization reaction between the PNA probes supportedon a support and the target nucleic acids; and a composition and a kit therefor.
申请人:Heekyung Park,Jaejin Choi
地址:Daejeon KR,Daejeon KR
国籍:KR,KR
代理机构:Clark & Brody
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