专利名称:Sequestrin
发明人:Patrick E. Duffy,Christian F. Ockenhouse申请号:US09351794申请日:19990713公开号:US06641815B2公开日:20031104
摘要:In this application is described the expression cloning and functional
characterization of the CD36-binding domain of Sequestrin. Sequestrin is a surface proteinof 215-250 kD size which does not vary in size between parasite strains. The Sequestringene appears to be single-copy-number within the genome; noncytoadherent laboratoryparasite strains carry the sequestrin gene but fail to express the protein. Sequestrin bindswith high affinity to CD36. Sequestrin protein and sequence can be used as a diagnostic,prognostic, and therapeutic tool.
申请人:THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OFTHE ARMY
代理人:Elizabeth Arwine,Charles H. Harris
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